Independence Blue Cross Becomes First Major Insurer To Cover Next-Generation Whole Genome Sequencing For A Variety Of Cancers

Philadelphia — Independence Blue Cross (Independence) announced today that it has entered into an agreement with NantHealth to cover next-generation whole genome sequencing for a variety of cancers. Independence will become the first major insurer to offer coverage for next-generation whole genome sequencing, which fully sequences thousands of genes in a single test, detecting DNA mutations that may serve as markers that inform decisions about optimal cancer therapy.

“Independence Blue Cross is committed to bringing state-of-the-art advances in oncology to our members and making care accessible and affordable,” said Daniel J. Hilferty, president and CEO, Independence Blue Cross.  “Decisions around cancer care are complex and personal. We’re focused on supporting Independence members and their oncologists by offering coverage for this innovative approach to treating cancer. Whole genome sequencing is one more option to help inform a personalized, effective treatment plan.”

Independence’s agreement with NantHealth involves a very specific and complex lab study related to cancer, next-generation whole genomic sequencing of tumor DNA, and related proteomic testing, for certain types of cancer. The test will be covered for members with specific conditions including rare cancers, tumors in children, metastatic cancer of unknown primary, primary brain cancer, triple negative breast cancer, and metastatic cancer where conventional therapies have been exhausted and patients remain candidates for further therapy. Coverage for the testing will be available to eligible members of Independence commercial plans in March 2016.

In addition to its coverage of full genomic testing for eligible members, Independence has joined the National Immunotherapy Coalition (NIC). Launching today, the NIC will be the nation’s most comprehensive cancer collaborative initiative, focused on accelerating the potential of combination immunotherapy as the next generation standard of care in cancer patients. The Coalition and its members will design, initiate and complete the Cancer Moon Shot 2020 Program, a series of randomized Phase II trials in 20,000 patients at all stages of disease in 20 tumor types within the next 24-36 months.

Independence members referred by their oncologist for participation in one of the approved Moon Shot 2020 clinical trials will be eligible for coverage for the routine patient care costs related to the trial. The coverage includes all routine services required for the patient — such as blood tests, supportive medications, and surgical interventions. Experimental drugs which are not approved by the FDA are generally covered by the study sponsor. Independence’s detailed coverage policy for clinical trials can be found at

“At Independence, we are committed to supporting Personalized Medicine, enabling patients and their physicians to make better informed decisions,” said Don Liss, M.D., vice president of clinical programs and policy at Independence. “The science around genomics and immunotherapy and their potential to advance cancer care is evolving. Entering into a relationship with NantHealth, and supporting the Cancer Moon Shot 2020 Program, are two ways that we can responsibly contribute to the evidence-base and – potentially – help to advance cancer care.”

About Independence Blue Cross
Independence Blue Cross is the leading health insurance organization in southeastern Pennsylvania. With our affiliates, we serve nearly 10 million people in 34 states and the District of Columbia, including 2.5 million in the region. For nearly 80 years, we have been enhancing the health and wellness of the people and communities we serve by delivering innovative and competitively priced health care products and services; pioneering new ways to reward doctors, hospitals, and other health care professionals for coordinated, quality care; and supporting programs and events that promote wellness. To learn more, visit Connect with us on Facebook at and on Twitter at @ibx. Independence Blue Cross is an independent licensee of the Blue Cross and Blue Shield Association. 

About Blue Cross Blue Shield Association

The Blue Cross and Blue Shield Association is a national federation of 34 independent, community-based and locally operated Blue Cross and Blue Shield companies that collectively provide health care coverage for one in three Americans. BCBSA provides health care insights through The Health of America Report series and the national BCBS Health Indexsm. For more information on BCBSA and its member companies, please visit We also encourage you to connect with us on Facebook, check out our videos on YouTube and follow us on Twitter.

The Blue Cross Blue Shield Association is an association of 35 independent, locally operated Blue Cross and/or Blue Shield companies.